[Microbiology] Atlas about Antibiotic Mechanisms of Action and Resistance

Atlas about Antibiotic Mechanisms of Action and Resistance, Antibiotic Mechanisms of Action and Resistance, Antibiotic , Mechanisms, of, Action, and, Resistance, atlas in medical, tuyenlab.net

Primary sites of antibacterial action for major classes of antimicrobial agents
Fig 1.  Primary sites of antibacterial action for major classes of antimicrobial agents. THFA, Tetrahydrofolic acid; DHFA, dihydrofolic acid; PABA, para-aminobenzoic acid.


The cell envelope structure of a gram-positive (left) and a gram-negative (right) bacterium.
Fig 2.  The cell envelope structure of a gram-positive (left) and a gram-negative
(right) bacterium.

Fig 3.  A diagram that demonstrates the structure of the peptidoglycan layer in
the cell wall of Escherichia coli. The amino acids in the cross-linking tetrapeptides may
vary among species. NAG, N-acetyl-D-glucosamine; NAM, N-acetyl-D-muramic acid.

Chemical structures of major classes of β-lactam antibiotics.
Fig 4.  Chemical structures of major classes of β-lactam antibiotics.

Sites of action of sulfonamides and trimethoprim and their effects on synthesis of essential amino acids and nucleic acids.
Fig 5.  Sites of action of sulfonamides and trimethoprim and their effects on synthesis of essential
amino acids and nucleic acids.

Active efflux in gram-negative bacteria mediated by transmembrane proteins located in cytoplasmic and outer membrane.
Fig 6.  Active efflux in gram-negative bacteria mediated by transmembrane proteins located in cytoplasmic and outer membrane. Emr/Mex, Multidrug transporter efflux system; ABC ATPase, ATP-binding cassette family pumps; ATP, adenosine triphosphate; ADP, adenosine diphosphate;
Tet A, tetracycline specific transporter pump; H+, efflux pumps driven by proton motive force mediated by the counterflow of protons.

 β-Lactamase hydrolyzes the β-lactam ring portion of the penicillin molecule.
Fig 7.  β-Lactamase hydrolyzes the β-lactam ring portion of the penicillin molecule. The hydrolysis results in the formation of penicilloic acid, which does not have antibacterial activity.

This is a part of the book : Textbook of Diagnostic Microbiology 4th edition 2011 of authors: Connie R. Mahon, Donald C. Lehman and George Manuselis. If you want to view the full content of the book and support author. Please buy it here: http://amzn.to/2ctxo02

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Atlas for Medical: [Microbiology] Atlas about Antibiotic Mechanisms of Action and Resistance
[Microbiology] Atlas about Antibiotic Mechanisms of Action and Resistance
Atlas about Antibiotic Mechanisms of Action and Resistance, Antibiotic Mechanisms of Action and Resistance, Antibiotic , Mechanisms, of, Action, and, Resistance, atlas in medical, tuyenlab.net
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